No they can not... Dont know why but they cant... Hope this helps you...

But on the bright side, the new nintedogs+cats for 3ds is able to breed, or so i've heard.
You have to have the 3ds and the game cost 40 bucks though...

Yeah you heard me nintendogs can have puppuies on nintendogs chiwawa and friends my
chiwawas had a puppy it said this as soon as i got on nintendogs it said ginger had a
puppy. The puppy has approached you for the first time it will take some time to bond to
it. I put the bond part in my own words hope it helps

I did think they could, but now i don't.
If you look on youtube, they say they have puppies but action reply is used to make their
dogs smaller to look like a puppy. Now this is just my opinion, they could have puppies,
but i think no.
And yes, i did try breeding but it didn't last long though.
Hope i helped!

Get 2 dogs (the same breed one girl one boy not the same color) if you have 3
Drop them in dog hotel so there would be space for puppy. No wal for them play with them
maximum 2min. No contest and dont brush their fur. Feed them only with dry food and milk.
İt would take a month or weeks