1. This requires a saved game to work, so either start a new game and reach a save point or use an old save.
2. Backup the files: gamestat.ini and game#.ini (where # is the number of the saved game from 0-9) from the Spider-Man 2 System directory.
3. Edit both files with notepad.exe (or equivalent).
4a. For Spider-Man 2 System gamestat.ini change the line:

MaxHealth=100 // 200 is upgraded value -->MaxHealth=1000 // 2000 is upgraded value

Now save the file.

4b. For Spider-Man 2 System game#.ini change the value:

Health=100MaxHealth=100 --> Health=1000 MaxHealth=1000

This will give you 1000 hit points 10x the standard. Use higher values if necessary, you can edit your current health at any time by reaching a save point and changing the line Health=### in the game#.ini to it's max value again. This doesn't effect enemy forces.