if u have the magic spell CRITICAL HIT use that with the best weapon u have

Just keep running wide circles around it and hitting her with strong ranged
weapons/abilities. If she hits you with a web strand and tries to pull you in, just run
in the opposite direction. You should just remain where you are. If she does get you
clse enough to hit you, beat her to the punch and use your strongest melee move on her and
she'll be "stunned" and let go of you.

Go on either side of her giant egg and use a range weapon or spell. She cant reach you but
the spiders can.

dude that is the antqueen not the spider(shelox)