Most people hate this skill because you never can seem to find what you want. Well I'm going to change that. This is what I did:
1. Buy Carin bolete cap and lady's smock leave for "The main Ingredient
2. Use the item dupe trick on these two items
3. Use mortal and pester and put both ingredients in
4.make potions until you have one of each item
5. Sell potions or use them for your own reasons
In about 1 hour you will be a Master Alchemist

This trick works for all alchemy levels novice and up

The dupe trick might freeze your game up so always save right before you do it.

This trick may not work for everyone considering that in June the makers fixed the item dupe glitch so some people can't do this trick

but for the rest of you when you become a master you will be able to make potions with 1 ingredient